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Increasing nuclease activity in β-toxin-positive S. aureus isolates. Nuclease activity was measured for all S. aureus isolates and correlated with β-toxin status of isolates as exemplified here for isolates of patients 8 and 12. The graph distinguishes β-toxin-negative and -positive isolates, showing an increase of nuclease activity in β-toxin-positive isolates over time (P < 0.001), as analyzed by GEE.
