TABLE 1.

CF patients’ demographics and clinical parameters

Patient	CF genotypea	Sexb	Agec (yr)	Mean lung function FEV1%predd	S. aureus persistence (yr)	No. of visits	No. of visits with exacerbationse	Mean S100 A8/A9 (ng/ml)f	Mean CRP (mg/dl)f	Mean IL-6 (pg/ml)f
1	F508del hetero	M	20	49.9	18	5	4	4,335.3	1.64	5.6
2	F508del homo	M	23	91.9	20	4	2	2,732.9	0.20	4.5
3	F508del homo	F	45	35.8	17	4	1	6,509.4	1.43	13.4
4	Other	M	19	78.0	19	4	1	1,066.4	0.28	1.6
5	Other	M	22	78.7	21	4	2	254.3	0.04	1.46
6	F508del homo	M	24	50.3	11	4	1	3,540.3	1.75	14.4
7	F508del hetero	F	40	75.4	18	4	1	1,622.2	0.54	5.0
8	F508del homo	M	18	66.9	14	3	0	2,240.4	0.09	3.8
9	F508del homo	M	29	61.1	10	5	2	8,469.9	1.54	14.0
10	F508del homo	F	16	56.3	15	4	1	3,782.0	0.52	5.6
11	F508del homo	M	23	89.9	15	5	1	3,145.0	0.22	3.9
12	other	M	37	29.6	14	5	4	4,828.1	2.51	20.8
13	F508del hetero	M	39	82.9	12	4	0	2,296.0	0.32	6.0
14	F508del homo	M	35	53.6	15	3	2	4,183.1	0.32	5.5

^aCFTR genotype of patients. F508del hetero, F508del heterozygous; F508del homo, F508del homozygous; Other, other mutations.

^bM, male; F, female.

^cAge at the beginning of the study.

^dMean lung function was calculated as a mean of the lung function data available throughout the study period.

^eVisits with exacerbation according to the Fuchs criteria for exacerbation (30).

^fMean values were calculated as a mean of all data available throughout the study period.