TABLE 2.

S. aureus characteristics and coinfection with P. aeruginosa

Patient	No. of S. aureus isolatesa	Dominant spa typeb	spa type	Related spa typec	PTd	MDRAe				SDIf		Coinfection with P. aeruginosag
						spa type	PT	Biofilm formation	Nuclease activity	spa type	PT
1	200	t091	2	0	2.4	0.02	0.35	0.02	0.01	0.08	0.54	New (no PA 3y)
2	160	t1577	2	0	4.5	0.03	0.28	0.00	0.01	0.10	0.58	No PA (4y)
3	160	t008	4	4	4	0.07	0.15	0.00	0.02	0.22	0.73	Chronic (17y)
4	160	t5430	6	4	4	0.11	0.28	0.00	0.04	0.40	0.72	No PA (5y)
5	160	t021	1	0	2.75	0.00	0.21	0.00	0.00	0.00	0.46	Chronic (6y)
6	160	t166	1	0	1.75	0.00	0.07	0.00	0.10	0.00	0.29	No PA (3y)
7	160	t206	6	3	4	0.10	0.13	0.08	0.08	0.48	0.64	No PA (5y)
8	120	t034	1	0	1.6		0.05	0.06	0.05	0.00	0.19	No PA (4Y)
9	200	t002	4	3	3.8	0.02	0.53	0.17	0.12	0.05	0.74	Chronic (6y)
10	160	t617	4	4	5	0.02	0.35	0.03	0.03	0.10	0.87	New (no PA 4y)
11	200	t091	2	2	4.8	0.02	0.33	0.09	0.02	0.03	0.74	New (no PA 4y)
12	200	t011	5	4	4	0.19	0.50	0.22	0.29	0.49	0.69	Chronic (15y)
13	159	t003	13	13	8.25	0.11	0.24	0.07	0.11	0.39	0.87	Chronic (8y)
14	120	t067	5	2	2	0.05	0.04	0.02	0.00	0.27	0.30	Chronic (15y)

^aNumber of collected S. aureus isolates from the respective patient from sputum cultures during the study, which have been further analyzed.

^bDominant spa type, which is present at all visits in a high percentage of isolates.

^cNumber of spa types related to the dominant spa type, in which mutations were observed resulting in a different spa type with close relation to the dominant spa type.

^dMean number of phenotypes (PTs) observed in sputa.

^eMean daily rate of alteration as described by Roden et al. (68).

^fSimpson’s diversity index.

^gPA, P. aeruginosa; y, years.