FIG 6.
C. auris pmr1Δ and van1Δ strains grow to lower burdens in the larval zebrafish hindbrain in the presence of neutrophils. Wild-type (A) or transgenic zebrafish expressing a dominant Rac2D57N mutation in neutrophils (B) were inoculated with C. auris by hindbrain injection. Fungal burden was quantified at 0, 1, 3, and/or 5 days postinfection by homogenizing whole larvae and plating for CFU. n = 20 to 24; experiments were performed in three replicates; mean with SEM are shown; *, P < 0.05; ns, not significant by Brown-Forsythe and Welch ANOVA with Dunnett’s T3 multiple comparisons to C. auris WT.