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. 2021 Jul 7;41(27):5876–5893. doi: 10.1523/JNEUROSCI.0284-21.2021

Figure 6.

Figure 6.

Dopamine-mediated hyperpolarization responses in dBNST neurons. A, Representative trace of dopamine release in response to optical stimulation (10 pulses, 20 Hz; blue). B, Representative averaged trace of slow outward current (pA) in response to optically stimulated dopamine release (n = 7 cells). C, Representative averaged trace of hyperpolarizing voltage (mV) response to optical stimulation at resting membrane potential, normalized for grouped average (n = 7 cells). D, Grouped data showing the absolute peak amplitude of current (pA) and voltage (mV) responses across cells. E, Grouped data showing the signal half-life for current (pA; B) and voltage (mV; C) responses across cells. F, The D2/D3 receptor antagonist raclopride (2 μm) significantly reduced the peak hyperpolarizing voltage (mV) amplitude in response to optical stimulation. *p < 0.05. G, Input resistance as a percentage of baseline resistance is significantly decreased following optical stimulation in cells with a slow current response (SC+) compared with cells with no slow current response (SC–). *p < 0.05. Bar graphs represent grouped mean with individual points overlain; error bars indicate +/- SEM.