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. 2021 Jul 8;16(7):e0252132. doi: 10.1371/journal.pone.0252132

Fig 4. In vitro assessment of MSI2 depletion in CRC cell lines.

Fig 4

(A-D) Averaged values for qRT-PCR (A, B) and Western blot (C, D) for MSI2, CDH1, TGFβ1, and ZO1 in control and MSI2-depleted RKO and HCT116 cell lines. (E-H) Cell viability (E, F) and clonogenic capacity (G, H) of control or MSI2-depleted RKO and HCT116 CRC cell lines. *, p<0.05; **, p<0.01; ***, p<0.001, in each case in reference to control-depleted cells; non-significant comparisons are not indicated.