Key Resources Table
Reagent type (species) or resource	Designation	Source or reference	Identifiers	Additional information
Cell line (M. musculus)	NIH/3T3	ATCC	Cat. #: ATCC CRL-1658	Immortalized Mouse fibroblast cells
Antibody	anti-PER1 (Rabbit polyclonal)	Created by J. Ripperger [53]		1:1000 (WB) 1:100 (IF)
Antibody	anti-Clock (Rabbit polyclonal)	Created by J. Ripperger [54]		1:1000 (WB)
Antibody	anti-HSP90 α/β (mouse, monoclonal)	Santa Cruz Biotechnology	Cat#: sc-13115 RRID:AB_627758	1:1000 (WB)
Antibody	anti-GFP (Rabbit polyclonal)	Abcam	Cat. #: ab6556 RRID: AB_305564	1:500 (IF)
Antibody	Anti-Cre recombinase monoclonal antibody (GT10212)	Thermo Fisher Scientific	Cat. #: MA5-27870 RRID: AB_305564	1:500 (IF)
Antibody	Alexa Fluor 488- AffiniPure Donkey Anti-rabbit IgG (H+L) (Donkey polyclonal)	Jackson Immunoresearch	Cat. #: 711-545-152 RRID: AB_2313584	1:500 (IF)
Antibody	Alexa Fluor 568- AffiniPure Donkey Anti-rabbit IgG (H+L) (Donkey polyclonal)	Thermo Fisher Scientific	Cat. #: A10037 RRID: AB_2534013	1:500 (IF)
Antibody	Alexa Fluor 647- AffiniPure Donkey Anti-mouse IgG (H+L) (Donkey polyclonal)	Jackson Immunoresearch	Cat. #: 711-605-151 RRID: AB_2340863	1:500 (IF)
Antibody	anti-mouse IgG–peroxidase, produced in rabbit	Sigma-Aldrich	Cat #: A9044 RRID: AB_258431	1:10000(WB)
Antibody	anti-rabbit IgG–peroxidase, produced in goat	Sigma-Aldrich	Cat#: A9169 RRID: AB_258434	1:10000(WB)
Chemical compound	2% Lidocain HCl	Bichsel	Zul Nr. 53570089
Chemical compound	Rimadyl (Caprofenum 50mg/ml)	Zoetis	Swissmedic: 54375018
Chemical compound	RTI-13951-33 hydrochloride	MedChemExpress	Cat. # HY-112612A
Chemical compound	cOmplete, EDTA-free Protease Inhibitor Cocktail	Roche Diagnostics GmbH	Cat. # 06538282001
Commercial assay, kit	RNeasy Micro Kit	Qiagen	Cat. # 74004
Commercial assay, kit	SuperScript II Reverse Transciptase	Invitrogen	Cat. # 18064022
Commercial assay, kit	KAPA PROBE FAST qPCR Master mix	Kapa biosystems	Cat. # KR0397
Commercial assay, kit	Lipofectamine 2000 Transfection Reagent	Thermo Scientific	Cat. # 11668019
Commercial assay, kit	Pierce Rapid Gold BCA Protein Assay Kit	Thermo Scientific	Cat. # A53225
Commercial assay, kit	Pierce ECL Western Blotting Substrate	Thermo Scientific	Cat. # 32106
Genetic reagent (M. musculus)	mPer1Brdm1	Zheng et al., 2001		PMID: 11389837
other	DAPI	Thermo fisher	Cat. #: D3571 RRID: AB_2307445	(1 μg/mL)
Recombinant DNA reagent	Adeno-associated viral vectors (AAV)	Viral Vector Facility (VVF) of the Zurich Neuroscience Centre (ZNZ)	v77 (different serotypes) v81-6 v229-6
Recombinant DNA reagent	Primers and TaqMan probes	Complete list provided in the paper
Software	Leica application Suite Advanced Fluorescence	Leica	Version 2.7.3.9723
Software	Prism	GraphPad	Version 7.0d
Software	Quantity one	Biorad	Version 4.6.2
Software	ImageJ	ImageJ	Version 1.51n
Software	Circ Wave	Roelof A. Hut	Version 1.4