. 2021 Jul 8;16(7):e0254229. doi: 10.1371/journal.pone.0254229

Table 3. Effect of the intervention on non-modified and modified mean QOC score totals and components, comparing the pulse oximetry and full oxygen system periods to baseline (see S3 Table for restricted analysis comparing full oxygen system period to pulse oximetry period).

	Severe pneumonia				Severe malaria				Diarrhoea with severe dehydration
	Non-modified¹		Modified²		Non-modified¹		Modified²		Non-modified¹
	aMD (95% CI)	p-value	aMD (95% CI)	p-value	aMD (95% CI)	p-value	aMD (95% CI)	p-value	aMD (95% CI)	p-value
Score total ³
Pulse oximetry	0.66 (0.22, 1.09)	0.003	-0.17 (-0.53, 0.19)	0.351	1.26 (0.85, 1.68)	<0.001	0.68 (0.35, 1.00)	<0.001	-0.29 (-0.78, 0.21)	0.259
Full O2 system	1.39 (1.08, 1.69)	<0.001	0.23 (-0.02, 0.48)	0.072	1.53 (1.23, 1.83)	<0.001	0.65 (0.41, 0.89)	<0.001	-0.12 (-0.46, 0.23)	0.501
Assessment component³
Pulse oximetry	0.41 (0.13, 0.69)	0.004	-0.19 (-0.44, 0.06)	0.138	0.43 (0.20, 0.66)	<0.001	-0.03 (-0.19, 0.13)	0.705	-0.25 (-0.60, 0.10)	0.163
Full O2 system	0.74 (0.54, 0.93)	<0.001	-0.05 (-0.22, 0.13)	0.601	0.67 (0.51, 0.83)	<0.001	-0.06 (-0.18, 0.06)	0.303	-0.20 (-0.44, 0.04)	0.097
Diagnosis component³
Pulse oximetry	-0.04 (-0.12, 0.04)	0.342	-	-	0.15 (0.06, 0.25)	0.002	-	-	-0.03 (-0.17, 0.11)	0.683
Full O2 system	-0.02 (-0.08, 0.04)	0.559	-	-	0.12 (0.04, 0.10)	0.002	-	-	-0.05 (-0.15, 0.05)	0.292
Treatment component³
Pulse oximetry	0.15 (-0.013, 0.31)	0.072	0.06 (-0.11, 0.22)	0.511	0.55 (0.33, 0.78)	<0.001	0.47 (0.27, 0.68)	<0.001	-0.01 (-0.27, 0.25)	0.942
Full O2 system	0.32 (0.20, 0.44)	<0.001	0.17 (0.05, 0.29)	0.006	0.56 (0.39, 0.73)	<0.001	0.46 (0.31, 0.61)	<0.001	0.10 (-0.08, 0.28)	0.264
Monitoring component³
Pulse oximetry	0.19 (0.001, 0.39)	0.049	0.04 (-0.11, 0.20)	0.601	0.12 (-0.04, 0.27)	0.139	0.07 (-0.06, 0.20)	0.832	-0.11 (-0.34, 0.11)	0.317
Full O2 system	0.37 (0.24, 0.51)	<0.001	0.13 (0.02, 0.24)	0.016	0.18 (0.07, 0.29)	0.002	0.13 (0.04, 0.22)	0.007	-0.002 (-0.16, 0.15)	0.976

Acronyms: aMD = adjusted mean difference

¹ Non-modified QOC scores include features related to pulse oximetry and oxygen system use

² Modified QOC scores exclude features related to pulse oximetry and oxygen system use

³ Total = mean out of 6 total points, Assessment = total out of 2 points, Diagnosis = total out of 1 point, Treatment = total out of 2 points, Monitor = total out of 1 point