Additional Table 1. Clinical and pathological characteristics of breast cancer patients, BRCA sequencing, and the multiplex ligation-dependent probe amplification (MLPA) results.

ID	Age Years	HT	HG	ER (%)	PR (%)	HER2	Ki67 (%)	Molecular Subtype	CS	FH	BRCA	MLPA
1	71	IDC	2	100	80	Neg.	25	Luminal B	III	Yes	wt	wt
2	80	IDC	2	80	80	Neg.	30	Luminal B	ND	Yes	BRCA2	wt
3	66	IDC	1	95	80	Neg.	15	Luminal B	II	Yes	wt	ND
4	61	IDC	2	95	Neg.	Neg.	20	Luminal B	II	Yes	wt	wt
5	61	IDC	2	100	100	Neg.	12	Luminal A	II	Yes	wt	wt
6	74	IDC	1	100	100	Neg.	10	Luminal A	I	Yes	wt	wt
7	66	IDC	2	60	66	Neg.	30	Luminal B	I	Yes	wt	wt
8	61	IDC	2	Pos.	Pos.	Neg.	30	Luminal B	III	Yes	wt	wt
9	73	IDC	2	100	100	Neg.	10	Luminal A	I	Yes	wt	wt
10	57	IDC	ND	90	70	Neg.	10	Luminal A	I	Yes	wt	wt
11	73	IDC	2	95	Neg.	Neg.	15	Luminal B	II	Yes	wt	wt
12	73	IDC	3	100	5	Neg.	ND	Luminal	I	Yes	wt	wt
13	59	IDC	1	Neg.	Neg.	Pos.	18	HER 2	III	Yes	wt	wt
14	62	IDC	2	90	70	Neg.	ND	Luminal	II	Yes	wt	wt
16	60	IDC	1	90	100	Neg.	8	Luminal A	II	Yes	wt	wt
17	56	IDC	3	Pos.	Pos.	Neg.	80	Luminal B	III	Yes	BRCA1	wt
18	56	IDC	3	Neg.	Neg.	Neg.	30	TN	I	Yes	wt	wt
19	63	IDC	2	10	Neg.	Neg.	20	Luminal B	I	Yes	wt	wt
20	65	IDC	2	50	Neg.	Neg.	30	Luminal B	II	Yes	wt	wt
21	67	IDC	1	100	100	Neg.	30	Luminal B	II	Yes	wt	wt
22	56	IDC	2	66	1	Neg.	30	Luminal B	II	Yes	wt	wt
23	62	IDC	2	95	1	Neg.	18	Luminal B	I	Yes	wt	wt
24	76	IDC	3	Neg.	Neg.	Pos.	40	HER2	III	Yes	wt	wt
25	60	IDC	2	Neg.	Neg.	Neg.	65	TN	ND	Yes	wt	wt
26	60	IDC	2	Pos.	Neg.	Neg.	30	Luminal B	II	Yes	wt	wt
27	56	IDC	2	Pos.	Pos.	Neg.	30	Luminal B	ND	Yes	wt	wt
28	63	IDC	2	66	66	Neg.	30	Luminal B	ND	Yes	wt	wt
29	58	IDC	2	Neg.	Neg.	Neg.	33	TN	ND	Yes	BRCA1	wt
30	62	IDC	1	100	Neg.	Neg.	5	Luminal A	III	Yes	wt	wt
31	60	IDC	2	66	66	Neg.	30	Luminal B	ND	Yes	wt	wt
32	56	IDC	1	90	70	Neg.	10	Luminal A	I	No	wt	wt
33	55	IDC	1	Neg.	Neg.	Neg.	ND	TN	I	No	wt	wt
34	61	IDC	2	95	15	Neg.	20	Luminal B	II	Yes	wt	wt
35	68	IDC	2	66	66	Neg.	10	Luminal A	II	Yes	wt	wt
36	63	IDC	1	90	80	Neg.	10	Luminal A	I	Yes	wt	wt
37	62	IDC	2	95	0,1	Pos.	40	Luminal B	I	Yes	wt	wt
38	59	IDC	2	40	75	Neg.	20	Luminal B	I	Yes	wt	wt
39	63	IDC	2	100	100	Neg.	13	Luminal A	II	Yes	wt	wt
40	63	IDC	2	100	30	Pos.	20	Luminal B	III	Yes	wt	wt
41	62	IDC	2	Pos.	Pos.	Pos.	ND	Luminal	II	Yes	wt	wt
42	77	IDC	3	Neg.	Neg.	Pos.	70	HER2	III	Yes	wt	wt
43	65	IDC	2	>50	>50	Neg.	5-30	Luminal	II	Yes	wt	wt
44	56	IDC	3	90	Neg.	Neg.	30-40	Luminal B	II	Yes	BRCA2	wt
45	64	IDC	2	Pos.	Pos.	Neg.	ND	Luminal	II	Yes	wt	wt
46	55	IDC	2	Neg.	Neg.	Pos.	10	HER2	III	Yes	wt	wt
47	58	IDC	3	Neg.	Neg.	Neg.	70	TN	III	Yes	wt	BRCA1
48	75	IDC	1	>66	>66	Neg.	<15	Luminal A	I	Yes	wt	ND
49	79	IDC	2	Neg.	Neg.	Pos.	40	HER2	II	Yes	wt	wt
50	80	IDC	2	Pos.	Pos.	Neg.	ND	Luminal	II	Yes	wt	wt

ID: Patient identification; HT: Histological type; HG: Histological grade; ER: Estrogen receptor; PR: Progesterone receptor; CS: Clinical stage; FH: Family history for breast and/or ovarian cancer; ND: Not determined; wt: Wild type; MLPA: Multiplex ligation-dependent probe amplification.