Table 4.
Analysis of the effects of compounds 3 and 11 on the cell cycle progression in HCT-116 and MCF-7 cells, respectively, using flow cytometry.
%G0/G1 | %S | %G2/M | %Pre/G1 | ||
---|---|---|---|---|---|
Cell cycle arrest analysis in HCT-116 (µM) | |||||
Control | 70.21 | 25.21 | 4.19 | 0.39 | |
Gefitinib | 48.37 | 13.34 | 21.71 | 16.49 | |
3 | 53.41 | 20.91 | 12.62 | 13.06 | |
Cell cycle arrest analysis in MCF-7 (µM) | |||||
Control | 66.42 | 27.37 | 3.66 | 0.55 | |
Gefitinib | 46.31 | 16.51 | 23.63 | 13.55 | |
11 | 47.11 | 21.36 | 15.28 | 16.25 |