Table 2. Distribution of genotypes (codominant Model) and alleles of TAP1 polymorphisms groups.
| Polymorphism | Cases n=46 | Controls n=92 | OR | 95% CI | p | ||
|---|---|---|---|---|---|---|---|
| n | % | n | % | ||||
| 1177A>G (rs1057141) | |||||||
| Genotype | |||||||
| AA | 23 | 50 | 56 | 60.9 | 1.0 | ||
| AG | 16 | 34.8 | 30 | 32.6 | 1.296 | 0.587-2.833 | 0.516 |
| GG | 7 | 15.2 | 6 | 6.5 | 2.805 | 0.824-9.807 | 0.098 |
| Allele | |||||||
| Aa | 62 | 67.4 | 142 | 77.2 | 1.0 | ||
| G | 30 | 32.6 | 42 | 22.8 | 1.633 | 0.93 – 2.85 | 0.086 |
| Total | 92 | 100 | 184 | 100 | |||
| 2090A>G (rs1135216) | |||||||
| Genotype | |||||||
| AA | 25 | 54.4 | 61 | 66.3 | 1.0 | ||
| AG | 14 | 30.4 | 29 | 31.5 | 1.176 | 0.524-2.597 | 0.685 |
| GG | 7 | 15.3 | 2 | 2.2 | 8.328 | 1.722-61.98 | 0.007 |
| Allele | |||||||
| Aa | 64 | 69.6 | 151 | 82.1 | 1.0 | ||
| G | 28 | 30.4 | 33 | 17.9 | 1.997 | 1.109-3.587 | 0.021 |
| Total | 92 | 100 | 184 | 100 | |||
Significant p values are shown in bold, and p-values < 0.05 were considered statistically significant; aReference category; OR = odds ratio; CI = confidence interval. The p-value was calculated by the Chi-squared test (χ2). The Akaike information criteria in the codominant model to rs1135216 genotype GG: 11.088