Table 3. Analysis of the inheritance models considering the SNPs (1177A>G, 2090A>G) in the TAP1 gene.
| SNPs | Genotype | Cases | Controls | OR | 95% CI | p | Akaike | ||
|---|---|---|---|---|---|---|---|---|---|
| n | % | n | % | ||||||
| 1177A>G (rs1057141) | |||||||||
| Dominant | AAa | 23 | 50 | 56 | 60.9 | 1.0 | |||
| AG+GG | 23 | 50 | 36 | 39.1 | 1.551 | 0.755-3.193 | 0.232 | ||
| Recessive | AA+AGa | 39 | 84.8 | 86 | 93.5 | 1.0 | |||
| GG | 7 | 15.2 | 6 | 6.5 | 2.553 | 0.778-8.591 | 0.121 | ||
| Additive | 0.647 | 0.382-1.095 | 0.105 | ||||||
| 2090A>G (rs1135216) | |||||||||
| Dominant | AAa | 25 | 54.4 | 61 | 66.3 | 1.0 | |||
| AG+GG | 21 | 45.7 | 31 | 33.7 | 1.647 | 0.793-3.421 | 0.180 | ||
| Recessive | AA+AGa | 39 | 84.8 | 90 | 97.8 | 1.0 | |||
| GG | 7 | 15.2 | 2 | 2.2 | 7.945 | 1.684-57.97 | 0.007 | 11.514 | |
| Additive | 0.526 | 0.297-0.930 | 0.027 | 18.436 | |||||
SNPs = single nucleotide polymorphisms; aReference category; OR = odds ratio, 95% CI confidence interval. Significant p values are shown in bold, and p-values <0.05 were considered statistically significant. The p-value was calculated by the Chi-squared test (c2). The Akaike information criteria were calculated for the polymorphisms presenting with more than one inheritance model and that had statistical significance.