Table 1. Correlation between clinicopathological parameters and the density of S100A9+ cells.
| Characteristics | No. N-S100A9+ (%) | No. T-S100A9+ (%) | ||||
| Low (No. 191) | High (No. 191) | P value* | Low (No. 191) | High (No. 191) | P value* | |
| Sex | ||||||
| female | 30 (7.85) | 14 (3.66) | 0.010 | 28 (7.33) | 16 (4.19) | 0.054 |
| male | 161 (42.15) | 177 (46.34) | 163 (42.67) | 175 (45.81) | ||
| Age, years | ||||||
| ≤ 50 | 97 (25.39) | 100 (26.18) | 0.759 | 95 (24.87) | 102 (26.70) | 0.474 |
| > 50 | 94 (24.61) | 91 (23.82) | 96 (25.13) | 89 (23.30) | ||
| HBsAg | ||||||
| negative | 23 (6.02) | 16 (4.19) | 0.237 | 20 (5.24) | 19 (4.97) | 0.866 |
| positive | 168 (43.98) | 175 (45.81) | 171 (44.76) | 172 (45.03) | ||
| AFP, ng/mL | ||||||
| ≤ 25 | 77 (20.16) | 60 (15.71) | 0.070 | 65 (17.02) | 72 (18.85) | 0.455 |
| > 25 | 114 (29.84) | 131 (34.29) | 126 (32.98) | 119 (31.15) | ||
| ALT, U/L | ||||||
| ≤ 40 | 117 (30.63) | 102 (26.70) | 0.121 | 106 (27.75) | 113 (29.58) | 0.469 |
| > 40 | 74 (19.37) | 89 (23.30) | 85 (22.25) | 78 (20.42) | ||
| Cirrhosis† | ||||||
| absent | 39 (10.43) | 42 (11.23) | 0.706 | 45 (12.03) | 36 (9.63) | 0.236 |
| present | 148 (39.57) | 145 (38.77) | 141 (37.70) | 152 (40.64) | ||
| Differentiation† | ||||||
| I + II | 154 (40.63) | 141 (37.20) | 0.131 | 151 (39.84) | 144 (37.99) | 0.248 |
| III + IV | 36 (9.50) | 48 (12.66) | 37 (9.76) | 47 (12.40) | ||
| Tumor multiplicity | ||||||
| single | 145 (37.96) | 135 (35.34) | 0.247 | 146 (38.22) | 134 (35.08) | 0.165 |
| multiple | 46 (12.04) | 56 (14.66) | 45 (11.78) | 57 (14.92) | ||
| Tumor size, cm | ||||||
| ≤ 5 | 117 (30.63) | 71 (18.59) | < 0.001 | 93 (24.35) | 95 (24.87) | 0.838 |
| > 5 | 74 (19.37) | 120 (31.41) | 98 (25.65) | 96 (25.13) | ||
| BCLC | ||||||
| A | 137 (35.86) | 108 (28.27) | 0.002 | 130 (34.03) | 115 (30.10) | 0.110 |
| B + C | 54 (14.14) | 83 (21.73) | 61 (15.97) | 76 (19.90) | ||
| TNM stage | ||||||
| I + II | 153 (40.05) | 122 (31.94) | < 0.001 | 142 (37.17) | 133 (34.82) | 0.305 |
| III + IV | 38 (9.95) | 69 (18.06) | 49 (12.83) | 58 (15.18) | ||
†Data were missing in these variables for some patients.
*χ2 test. Significant P values (< 0.05) are shown in bold.