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. 2021 Jun 16;13(12):16287–16315. doi: 10.18632/aging.203157

Table 3. Univariate COX regression analysis of m6A regulatory genes for endometrial cancer patients' overall survival (OS) and disease-free survival (DFS).

OS DFS
Variable HR P Lower 95%CI Upper 95%CI HR P Lower 95% CI Upper 95%CI
Age 1.035 0.001 1.015 1.056 1.009 0.477 0.984 1.034
Stage 4.085 0.001 2.673 6.243 2.682 0.001 1.552 4.634
Grade 3.778 0.001 2.133 6.693 1.468 0.180 0.837 2.574
Invasion 1.012 0.001 1.008 1.016 1.009 0.079 0.999 1.018
Lymph Metastasis 0.973 0.011 0.952 0.994 1.006 0.589 0.983 1.030
PIK3CA 0.680 0.092 0.434 1.066 0.637 0.132 0.354 1.146
KRAS 0.571 0.111 0.286 1.138 0.640 0.304 0.274 1.498
POLE 0.640 0.184 0.331 1.237 0.511 0.153 0.203 1.283
TP53 1.326 0.198 0.863 2.037 1.407 0.229 0.807 2.453
PIK3R1 1.322 0.233 0.836 2.090 1.034 0.915 0.553 1.934
FBXW7 1.210 0.490 0.704 2.080 1.180 0.651 0.576 2.417
PTEN 0.867 0.507 0.568 1.323 0.880 0.642 0.513 1.509
PPP2R1A 0.981 0.950 0.544 1.771 0.351 0.078 0.109 1.125
W-E- 2.337 0.0001 1.533 3.564 1.831 0.037 1.036 3.236

Note: R-W-: m6A regulator alteration (Writer loss + Eraser loss); HR: (95% CI).