Table 3. Relationship between IL6/SATA-3 signaling pathway and survival time in NPC patients.
Genes/ Proteins | Median survival time (month) | p |
IL-6 | < 0.001 | |
Positive | 33 | |
Negative | 71 | |
STAT3 | < 0.001 | |
Positive | 31 | |
Negative | 66 | |
p-STAT3 | < 0.001 | |
Positive | 30 | |
Negative | 65 | |
JAK2 | < 0.001 | |
Positive | 30 | |
Negative | 59 | |
p-JAK2 | < 0.001 | |
Positive | 31 | |
Negative | 64 | |
CyclinD1 | < 0.001 | |
Positive | 30 | |
Negative | 63 |
Abbreviations: NP: nasopharyngeal carcinoma; IL-6: interleukin-6; JAK2: Janus kinase 2; STAT3: Signal transducers and activators of transcription 3.