Table 3. Clinical measures of 72 elderly patients with COVID-19 who received late HFNC group.
| Clinical measures |
Total (n=72) |
Non-survivors (n=22) |
Survivors (n=50) |
P valuea |
| Heart rate, beats per min | 92 (68-139) | 93 (62-141) | 91 (65-132) | 0.287 |
| Systolic blood pressure on admission, mmHg | 134 (115-158) | 138 (110-163) | 130 (105-165) | 0.565 |
| Diastolic blood pressure on admission, mmHg | 75 (66-115) | 77 (63-115) | 75 (65-110) | 0.431 |
| SOFA score on admission | 4 (3-6) | 5 (3-7) | 4 (3-6) | 0.127 |
| APECHE II score on admission | 14 (12-19) | 15 (12-19) | 14 (12-17) | 0.602 |
| Comorbidities per person | 1.4 (0.8-1.6) | 1.6 (0.9-1.7) | 1.3 (0.6-1.6) | 0.211 |
| Haemoglobin concentration on admission, g/L | 125 (97-136) | 123 (92-138) | 125 (98-143) | 0.341 |
| Lymphocyte count on admission, ×109/L | 0.75 (0.35-1.65) | 0.73 (0.32-1.63) | 0.76 (0.39-1.71) | 0.791 |
| Platelet count on admission, ×109/L | 165 (123-223) | 165 (121-231) | 167 (126-226) | 0.463 |
| Total bilirubin concentration on admission, μmol/L | 9.3 (6.7-15.6) | 9.6 (6.4-16.2) | 9.2 (6.5-14.3) | 0.358 |
| Serum creatinine concentration on admission, μmol/L | 78.7 (55.6-101.2) | 83.5 (70.2-102) | 71.2 (53.3-91.5) | 0.212 |
| Lactate concentration on admission, mmol/L | 1.7 (1.5-3.2) | 1.7 (1.3-3.1) | 1.6 (1.3-3.2) | 0.411 |
| Ratio of PaO2 to FiO2, mmHg on admission | 173 (155-197) | 174 (132-198) | 172 (152-195) | 0.637 |
| Invasive Mechanical ventilation | 38 (52.7%) | 22 (100%) | 16 (32%) | <0.001 |
| FiO2 during hospitalization | ||||
| 100% more than 72 hours continuously, n | 4 (5.5%) | 4 (18.1%) | 0 | 0.011 |
| >80% more than 72 hours continuously, n | 16 (22.2%) | 12 (54.5%) | 4 (8%) | <0.001 |
| >60% more than 72 hours continuously, n | 32 (44.4%) | 22 (100%) | 12 (24%) | <0.001 |
Data are median (IQR), n (%), or n/N (%). FiO2=fraction of inspired oxygen. HFNC=high flow nasal cannula. PaO2=partial pressure of oxygen. SOFA score= sequential organ failure assessment score. APECHE II scores= acute physiology and chronic health evaluation II score.
aP values indicate differences between Non-survivors and Survivors.
P < 0.05 was considered statistically significant.