Table 1. The regulation network of miRNAs and ADAM17 in different human diseases.

miRNAs targeted ADAM17	Regulation network	Pathology conditions	Reference
miR-152	miRNA↑, ADAM17↓	NSCLC	Su et al. 2014
miR-338	miRNA ↓, ADAM17↑	NSCLC Neuroblastoma. Gastric Cancer. HCC	Chen et al. 2013; Hong et al. 2020; Sun et al. 2015; Wang et al. 2015
miR-122	miRNA ↓, ADAM17↑	HCC	Li et al. 2012; Jopling 2012; Thakral et al. 2015
miR-708	miRNA ↓, ADAM17↑	Idiopathic Pulmonary Fibrosis	Liu et al. 2018
miR-143, miR-145 miR-148a, miR-152	miRNA ↓, ADAM17↑	Colon Cancer	Dougherty et al. 2020
miR-326	miRNA↑, ADAM17↓	Hashimoto‘s Thyroiditis	Liu et al. 2020
miR-148	miRNA ↓, ADAM17↑	Nasopharyngeal Carcinoma	Shi et al. 2020
miR-145	Feedback Loop	Renal Cell Carcinoma	Doberstein et al. 2013