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. 2021 Jun 30;11(2):994–1005. doi: 10.3126/nje.v11i2.36682

Table 1.

Summary of literature on the effect of cooking in iron containing cookware and using iron ingot on anemia status of the study participants

Author Year Country Study design and duration Participant Characteristics Intervention Findings
Borigato EV, et al. [25] 1998 Brazil RCT++
8 months
n= 45
Age= 4 months
##M:F-10:12 (Fe* pot)
M:F-11:12 (Al# pot)
Infants consumed food prepared in Fe pot or Al pot Mean hemoglobin (+0.52g/l) in Fe pot significantly increased as compared to Al pot (-0.74g/dl)
Adish AA, et al. [27] 1999 Ethiopia RCT
12 months
n= 407
Age= 2-5 years
M:F-99:96 (Fe pot)
M:F-106:106 (Al pot)
Three meals cooked in Al, clay & Fe pot.
Consumption of food prepared in Fe & Al pots
More increase in crude Fe content in meat and vegetables than legumes
Hb+ increased by 1.7g/dL from baseline (p=0.008), proportion of IDA** reduced from 57% to 13%
Geerligs, et.al. [23] 2003 Malawi RCT
5 months
n= 322
Age: <12 yrs
M:F-0.9 (Fe pot)
M:F-1.1 (Al pot)
Age: >12yrs
M:F- 0.6 (Fe pot)
M:F- 0.7 (Al pot)
Fe or Al cooking pot assigned for cooking < 12 years: No increase in Hb,
> 12 years: Significant Hb rise at 6 weeks (+0.36g/dl) & 20 weeks (+0.53g/dl) in consistent Fe pot users (p<0.05)
Geerligs PP, et al. [24] 2004 Malawi Experimental laboratory trial Three Malawian meals prepared in two Fe pots and a glass pot Fe content improved from 3.15 μg to 147.32 μg/g in food, when cooked in Fe pot
Continuous cooking further increased Fe content by 2.9 μg to 20.1 μg Fe/g.
Sharieff W, et.al [28] 2007 Benin, Africa Cluster RCT
6 months
n=71 children, age= 6-24 months;
n=92 adolescent girls,
age=11-15 years;
n= 131women,
age=15-44 years
Two groups used cast Fe or blue steel pots and controls had Fe supplements Insignificant differences in mean Hb or IDA among groups, SF+++ was higher in control group (p<0.0001)
Charles CV, et al. [19] 2010 Cambodia RCT
6 months
n=189 women
Age= >16y with haematocrit >30%
3 groups: control, received Fe fish with no follow up and received Fe fish with follow up No significant change in Hb
Charles CV, et al.
[20]
2011 Cambodia Experimental study - 4 groups: Controls: glass pot and Al pot; glass pot with Fe fish; and Al pot with Fe ingot Use of iron ingot while making water and soup samples met more daily iron needs
Charles CV, et al. [21] 2015 Cambodia RCT
12 months
n=310
pre- and post-menopausal women
3 groups: Fe ingot, Fe ingot plus nutrition education, and untreated control group Mean Hb concentration varied by 1.18 g/dL across control and treatment group (p<0.001)
IDA reduced by 46% in intervention group
Kulkarni SA, et al. [18] 2013 India Randomised trial
4 months
n= 27 pre-schoolers, mean age 2.9±0.9y
M:F- 12:15
Supplementation with a snack cooked in Fe pot, for 5 days/week Hb improved from 10.1±1.6 to 10.9±1.7 g/dL (p<0.001)
IDA reduced by 19%
Rappaport AI, et al. [22] 2017 Cambodia RCT
12 months
n=327 women, mean age 32 years 3 groups: iron-ingot, iron-supplement (18 mg/d), and control group Insignificant differences in mean Hb concentration among iron-supplement or ingot group compared with control
Arcanjo FPN, et al. [26] 2017 Brazil Cluster RCT
16 weeks
n=175 preschoolers
Age= < 59 months
M:F- 52:41 (Fe pot)
M:F- 48:34 (Al pot)
Consumption of food cooked in Fe pot or Al pot No significant increase in Hb for non-IDA children, Hb (Fe vs. Al): +1.69g/dl vs. +1.10g/dl for anemic children
No IDA in iron pot group
Xing Q, et al. [29] 2017 China Experimental study Panel of 12 trained
tasters (4 males & 8 females)
Five pea samples soaked in deionized water, boiled in Fe pot & clay pot with variable iron content (0, 0.05, 0.50, 5.00 mg/L FeSO4) and freeze dried. Pea pastes in Fe pot had 3.3 times higher Fe content (21.4±1.0 mg) than clay pot (p<0.05), more FeSO4 (wt/vol), more Fe content in pea
Cheng YJ, et al. [30] 1991 USA Experimental study - Fe content compared in raw sauce samples, sauce prepared in Fe pot and non Fe pot Apple sauce (Fe pot vs. non Fe pot vs. raw): 6.26mg vs. 0.18mg vs. 0.26mg/100g (p>0.05),
Spaghetti sauce (Fe vs. non-Fe pot vs. raw):
2.10mg vs. 0.44mg vs. 0.22mg/100 g (p<0.05)

*Fe: Iron,

+Hb: Hemoglobin,

++RCT: Randomised control trial,

#Al: Aluminium,

**IDA: Iron deficiency anemia,

+++SF: Serum ferritin,

##M:F : Male: female ratio in study