Table 2.
Adjusted means of phthalate biomarkers, at baseline, stratified by quartile of total hip bone mineral density, N = 1255
| Total hip BMD, g/cm2 | |||||
|---|---|---|---|---|---|
| 1st quartile ≤ 0.765 N = 314 | 2nd quartile 0.766-≤ 0.85 N = 311 | 3rd quartile 0.851-≤ 0.94 N = 309 | 4th quartile ≥ 0.95 N = 311 | ||
| Phthalate biomarker | Geometric mean (SD)a | P | |||
| MEP, ng/mL | 72.20 (1.64) | 83.94 (1.67) | 87.31 (1.79) | 99.92 (1.90) | .33 |
| MBzP, ng/mL | 10.72 (1.70) | 12.45 (1.71) | 12.32 (1.85) | 13.69 (1.95) | .34 |
| MCOP, ng/mL | 3.27 (1.54) | 3.85 (1.54) | 4.02 (1.64) | 4.55 (1.72) | .05 |
| MCNP, ng/mL | 2.53 (1.45) | 2.84 (1.44) | 2.91 (1.52) | 3.15 (1.57) | .25 |
| MCPP, ng/mL | 3.12 (1.60) | 3.44 (1.61) | 3.32 (1.72) | 3.52 (1.81) | .03 |
| ΣDBP, µmol/L | 0.12 (1.75) | 0.13 (1.76) | 0.13 (1.92) | 0.14 (2.03) | .03 |
| ΣDiBP, µmol/L | 0.01 (1.71) | 0.01 (1.72) | 0.01 (1.87) | 0.01 (1.98) | .76 |
| ΣDEHP, µmol/L | 0.16 (1.59) | 0.18 (1.59) | 0.19 (1.70) | 0.21 (1.78) | .61 |
Abbreviations: BMD, bone mineral density; DBP, di-n-butyl phthalate; DEHP, di(2-ethylhexyl) phthalate; DiBP, di-isobutyl phthalate; MBzP, monobenzyl phthalate; MCNP, mono carboxyisononyl phthalate; MCOP, monocarboxyoctyl phthalate; MCPP, mono-3-carboxypropyl phthalate; MEP, monoethyl phthalate.
a Geometric means estimated from regression models adjusting for age, creatinine, and race/site.