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. 2021 Jun 30;2021:7362233. doi: 10.1155/2021/7362233

Figure 2.

Figure 2

Upregulation of sestrin2 can inhibit the abilities of proliferation and migration of pancreatic cancer cells. The changes in the migration ability of the PANC-1 cell-sestrin2 overexpression group (sestrin2+) and sestrin2 knockdown group (sestrin2-) (a); the distance change of the migration is presented in the form of a histogram (b); data are represented as the mean ± SEM (n = 3). ∗P < 0.05 compared with control groups, ∗∗P < 0.005 compared with control groups. The changes in the migration ability of the CFPAC-1-sestrin2 overexpression group (sestrin2+) and sestrin2 knockdown group (sestrin2-) (c); the distance change of the migration is presented in the form of a histogram (d); data are represented as the mean ± SEM (n = 3). ∗∗P < 0.005 compared with control groups; the real-time cell analysis technology was utilized to examine the ability of proliferation of PANC-1 and CFPAC-1 cells after being infected with sestrin2 overexpression/knockdown lentivirus (e, f).