Table 1.
Characteristics of subjects with COVID-19 and peripheral arterial complications.
| NAME OF THE AUTHOR | PLACE | NO. OF PATIENTS | AGE | GENDER |
COMORBIDITY |
DURATION OF SYMPTOMS (IN DAYS) | TREATMENT |
OUTCOME | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DM | HTN | CAD | OBESITY | Others | ANTIBIOTICS | ANTIVIRAL | ANTICOAGULANT | OTHER | ||||||||
| 1 | Zhang et al. [7] | CHINA | n = 7 | 71 | F | – | – | – | – | – | 11 | – | – | Y (n = 6) | – | 5 DEATH 2 IMPROVED |
| 63 | F | – | – | – | – | – | 13 | – | – | – | ||||||
| 59 | M | Y | Y | – | – | – | 11 | – | – | – | ||||||
| 49 | M | – | – | – | – | – | 7 | – | – | – | ||||||
| 56 | M | Y | Y | Y | – | – | 16 | – | – | – | ||||||
| 65 | M | – | Y | – | – | Cerebral Infarction | 13 | – | – | – | ||||||
| 56 | F | – | – | – | – | – | 3 | – | – | – | ||||||
| 2 | Novara et al. [8] | ITALY | n = 1 | 78 | F | – | Y | Y | – | Diverticulosis, Brady Arrhythmia | – | – | Y | Y | Amiodarone | DEATH |
| 3 | Alonso et al. [9] | SPAIN | n = 24 | AGE-44-78 Mean = 62.4 |
F:M 7:17 |
Y n = 7 | Y n = 15 | Y n = 8 | Y n = 8 | Dyslipidemia, Cancer, Autoimmune Disease Etc |
– | Y | Y | Y | Interferon, Glucocorticoids, Tocilizumab, Cyclosporine, Colchicine |
3 DEATH 21 IMPROVED |
| 4 | Mathilde et al. [10] | GERMANY | n = 1 | 73 | F | Y | Y | – | Y | Peripheral Arteriosclerosis, Pulmonary Disease, Lichen Simplex Chronicus |
– | Y | – | Y | – | IMPROVED |
| 5 | Khalid et al. [11] | UAE | n = 1 | 41 | M | Y | – | – | – | – | 14 | – | Y | Y | Tocilizumab, Interferon Beta |
AMPUTATION |
| 6 | Bamgboje et al. [12] | USA | n = 1 | 61 | M | – | Y | – | – | – | 14 | Y | Y | Y | – | IMPROVED |
| 7 | Singh et al. [13] | India | n = 1 | 64 | F | – | – | – | – | Venous Insufficiency, Vertigo, Migraine Headaches, Hypothyroidism, Tobacco Abuse |
– | Y | Y | Y | Apixaban | IMPROVED |
| 8 | Ramachandran et al. [14] | India | n = 1 | 44 | M | Y | – | – | – | – | 3 | Y | – | Y | Npwti, Pirfenidone |
AMPUTATION |
| 9 | Shubhra et al. [15] | India | n = 1 | 65 | M | – | – | – | – | – | 10 | Y | – | Y | Aspirin, Cilastazole, Inj. Pentoxifylline |
DEATH |
| 10 | Chaudhary et al. [16] | India | n = 1 | 8 | M | – | – | – | – | Red Eyes And Generalized Erythematous Rash | 7 | Y | IVIG, Methylprednisolone, Prednisone, Ceftriaxone, Aspirin |
IMPROVED | ||
| 11 | Adekiigbe et al. [17] | USA | n = 1 | 47 | M | Y | – | – | – | Chronic Back Pain | 10 | y | Y | Azithromycin, Ceftriaxone, Apixaban, Methylprednisolone, |
AMPUTATION | |
| 12 | Baccellieri et al. [18] | Italy | n = 1 | 67 | M | – | Y | – | Y | – | 5 | Y | IMPROVED | |||
| 13 | Chun et al. [19] | USA | n = 1 | 51 | M | – | – | – | – | Congenital Tricuspid Atresia, Pulmonary Stenosis | 2 | Y | AMPUTATION | |||
| 14 | Sores et al. [20] | Brazil | n = 1 | 67 | M | Y | Y | – | – | Smoker | – | Y | Y | Y | Corticosteroid | DEATH |
| 15 | Qian et al. [21] | China | n = 1 | 53 | M | – | – | – | – | – | 9 | Y | Y | Y | IMPROVED | |
| 16 | Martino et al. [22] | Italy | n = 1 | 86 | F | – | – | – | – | Acute Coronary Syndrome | – | Y | AMPUTATION | |||
| 17 | Ilonzo et al. [23] | USA | n = 4 | 62 | M | Y | Y | – | – | CKD, Smoker, Chronic Pulmonary Disease | 2 | Y | AMPUTATION | |||
| 79 | M | – | Y | – | – | Gastroesophagal Reflux | 14 | Y | AMPUTATION | |||||||
| 69 | F | Y | Y | – | – | Hyperlipdemia | 2 | Y | AMPUTATION | |||||||
| 89 | F | – | – | – | – | CKD, Atrial Fibrillation |
– | Y | AMPUTATION | |||||||
| 18 | Valle et al. [24] | Spain | n = 3 | – | – | – | – | – | – | – | 17 | Y | IMPROVED | |||
| – | – | – | – | – | – | – | 24 | Y | IMPROVED | |||||||
| – | – | – | – | – | – | – | 28 | Y | IMPROVED | |||||||
| 19 | Mascia et al. [25] | Italy | n = 14 | AGE-65-81 Mean = |
F:M – |
Y n = UK | Y n = UK | Y n = UK | Y n = UK | CKD, Smoking, Dyslipidemia | – | Y | DEATHS n = 2 IMPROVED n = 1 UKNOWN n = 11 |
|||
| 20 | Etkin et al. [26] | USA | n = 49 | AGE-58-75 Mean = |
F:M 12:37 |
Y n = 17 | Y n = 26 | Y n = 8 | Y n = 28 | CKD | Mean: 6 | Y | DEATHS n = 21 IMPROVED n = 25 UKNOWN n = 3 |
|||
| 21 | Perini et al. [27] | Italy | n = 2 | 53 | M | – | – | – | – | – | 7 | Y | DEATH n = 1 IMPROVED n = 1 |
|||
| 37 | M | – | – | – | – | – | Y | |||||||||
| 22 | Maureree et al. [28] | USA | n = 1 | 60 | M | – | Y | – | Y | – | 10 | Y | IMPROVED | |||
| 23 | Borrelli et al. [29] | Italy | n = 2 | 54 | M | – | – | – | – | Dyslipidemia | 1 | Y | Clopidogrel, Aspirin |
IMPROVED | ||
| 58 | M | Y | Y | – | – | – | 1 | Y | IMPROVED | |||||||
| 24 | Singh et al. [30] | USA | n = 3 | 71 | F | – | – | – | – | Parkinson, Dementia, Depression | – | Y | DEATH | |||
| 70 | M | – | Y | – | – | – | – | Y | IMPROVED | |||||||
| 70 | F | Y | Y | – | – | – | 7 | Y | IMPROVED | |||||||
| 25 | Kathryn et al. [31] | USA | n = 2 | 70 | F | – | – | – | – | – | 7 | Y | Apixaban | DEATH | ||
| 43 | M | – | Y | – | Y | Hyperlipidemia | 7 | Y | Y | IMPROVED | ||||||
| 26 | Veyre et al. [32] | France | n = 1 | 24 | M | – | – | – | – | – | – | Y | Aspirin | IMPROVED | ||
| 27 | Khattab et al. [33] | Egypt | n = 3 | 75 | F | – | Y | – | – | Atrial Fibrillation | – | Y | Catecholamine | DEATH | ||
| 76 | F | Y | Y | – | – | – | – | Y | IMPROVED | |||||||
| 73 | F | – | – | – | – | Non-Hodgkin Lymphoma | – | Y | DEATH | |||||||
| 28 | Ali et al. [34] | USA | n = 1 | 74 | M | Y | – | – | – | – | Y | Argatroban | AMPUTATION | |||
| 29 | Muhammed et al. [35] | UK | n = 1 | 49 | M | – | – | – | – | – | Y | Y | Aspirin, Atorvastatin |
IMPROVED | ||
| 30 | Patel et al. [36] | USA | n = 1 | 73 | M | – | Y | – | – | Smoker | Y | DEATH | ||||
| 31 | Showers et al. [37] | USA | n = 1 | 63 | F | Y | Y | – | – | Charcot Foot, Asthma | Y | Y | Aspirin, Atorvastatin, , Methylprednisolone, |
AMPUTATION | ||
CAD: Chronic Artery Disease; CKD: Chronic Kidney Disease; DM: Diabetes mellitus; HTN: Hypertension; IVIG: Intravenous immunoglobulin.