Table 1.
Association Analysis of CDH23 Variant rs769896655 With Schizophrenia
| Variant | Subjects | Sample Size (n) | Alternate Allele (A) | Reference Allele (G) | P Value | Odds Ratio | 95% Confidence Interval | Minor Allele Frequency |
|---|---|---|---|---|---|---|---|---|
| CDH23 rs769896655 (Pro251Pro) chr10:71570918 G/A (GRCh38) | Schizophrenia | 2011 | 4 | 4018 | .0458 | 3.901 | 1.241–14.28 | 0.00099 |
| Controls | 11,759 | 6 | 23,512 | 0.00026 | ||||
| Controls (RIKEN) (Japanese) | 2170 | 2 | 4338 | 0.00046 | ||||
| ToMMo 8.3KJPN (Japanese) | 8380 | 3 | 16,757 | 0.00018 | ||||
| HGVD (Japanese) | 1209 | 1 | 2417 | 0.00041 |
Note: RIKEN: Schizophrenia and controls sampled from Honshu area of Japan (the main island of Japan).
ToMMo 8.3KJPN: Tohoku Medical Megabank Organization (https://jmorp.megabank.tohoku.ac.jp/202008/downloads#variant).
HGVD: The Human Genetic Variation Database Kyoto (http://www.hgvd.genome.med.kyoto-u.ac.jp/index.html).