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. 2021 Jun 17;49(12):6804–6816. doi: 10.1093/nar/gkab493

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Graphical Abstract — Single-molecule observation of the DnaB helicase in E. coli DNA replication shows a single, stably-integrated helicase supports replication, with additional helicases able to interact via available τ subunits.