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. 2021 May 12;49(12):6638–6659. doi: 10.1093/nar/gkab334

Figure 2.

Figure 2.

Overview of sequence-specific methodologies discussed in this review for targeting G4-forming sequences using synthetic oligonucleotides or mimics thereof. (A) Targeting flanking regions (i) and loops (ii). (B) Sequence-specific G4-disruption using C-rich probes. (C) G-rich synthetic probes for strand invasion approaches (i) or intermolecular quadruplex formation (ii).