Fig. 3.

Exploratory biomarker analysis by confirmed best overall response to bintrafusp alfa per independent review committee assessment. a Immune phenotype analysis. b Gene expression analysis; 2 patients with confirmed best overall responses of PD were not included in the RNAseq analysis due to failing QC. CR complete response, IFNG interferon gamma, NE not evaluable, PD progressive disease, PR partial response, QC Quality control, RNAseq RNA sequencing, SD stable disease, TGFB1 transforming growth factor-β 1, TPM transcript per million, TWIST1 twist family bHLH transcription factor 1, VIM vimentin