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. 2021 Apr 29;35(4):745–758. doi: 10.1007/s10557-021-07189-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Cardiac mechanical parameters following 20-min perfusion with cardioprotective agents. Heart was subjected to saline (as control group), KH176m (10 μM), or MPG (1mM) for 20min prior to ischemia. For all parameters, the change at T=20 min relative to the value at T= 0 min is depicted. (a) End-diastolic pressure (EDP), (b) heart rate (HR), (c) rate pressure product (RPP), (d) maximum contraction rate of the left ventricle (+dp/dt), (e) maximum relaxation rate of the left ventricle (-dp/dt), and (f) perfusion pressure (Pperf). *P<0.05, **P<0.01, ***P<0.001 vs control group