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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Nature. 2021 Jun 2;595(7866):295–302. doi: 10.1038/s41586-021-03609-w

Extended Data Figure 3. Reverse-phase high performance liquid chromatography (HPLC) analysis of erythroid cells derived from in vitro differentiation of edited SCD patient CD34+ HSPCs.

Extended Data Figure 3.

Reverse-phase HPLC chromatograms of erythroid cell lysates at culture day 18, with β-like globins and their associated fractions marked near the associated peak. Data from the most efficiently edited donor is shown. Red arrows indicate the start and end of globin chain peaks.