Microneedle array patch. (A) The size of the microneedle array patch; (B) Configuration of the microneedle array patch and (C) Structure of a single microneedle model. (Reprint from Y. Deng, J. Chen, Y. Zhao, X. Yan, L. Zhang, K. Choy, J. Hu, H.J. Sant, B.K. Gale, T. Tang, Transdermal Delivery of siRNA through Microneedle Array, Scientific Reports 6 (2016) 21422, under the terms of the Creative Commons CC BY license).