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. 2021 May 10;16(4):517–527. doi: 10.1007/s11523-021-00816-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 4 — Kaplan–Meier overall survival in patients with right-sided colorectal cancer [CRC] (dotted line) and in patients with left-sided CRC (continuous line) in the exploratory and validation cohorts. a In the exploratory cohort, median overall survival was 12.5 months (95% confidence interval [CI] 9.9–19.0) vs 8 months (95% CI 5.9–9.8) in patients with left-sided CRC and in patients with right-sided CRC, respectively (hazard ratio: 0.5; p = 0.0232). b In the validation cohort, median overall survival in patients with right-sided CRC (dotted/green line) and in patients with left-sided CRC (continuous/blue line) is shown. Median overall survival was 16.0 months (95% CI 13.5–28.0) vs 8.9 months (95% CI 3.4–9.0) in patients with left-sided CRC and in patients with right-sided CRC, respectively (hazard ratio: 0.37; p = 0.0670)