Fig. 1.

Summary of patient diagnosis for 47 samples collected by nucleolar pattern on indirect immunofluorescence (IIF) using HEp-2 cells with suspected anti-fibrillarin antibodies. The most prevalent diagnosis was systemic sclerosis (SSc, n = 26, 55%). Other diseases included systemic lupus erythematosus (SLE, n = 3, 6%), Raynaud’s phenomenon (RP, n = 1, 2%), and Sjögren’s syndrome (SjS, n = 3, 2%). Eleven of the patients remain unresolved without clinical diagnosis (24%) and 5 patients (11%) made up other diseases (Crohn’s disease, n = 2, Devic’s disease, n = 1, and cancer, n = 2)