Table 4.
Differentially down-regulated circRNAs in serum exosomes of patients with sepsis.
| circRNA | Alias | P-value | FDR | FC (abs) | chrom | circRNA_type | best_transcript | GeneSymbol |
|---|---|---|---|---|---|---|---|---|
| hsa_circRNA_006750 | hsa_circ_0006750 | 0.037575777 | 0.431741635 | 1.5167592 | chr10 | Exonic | NM_015188 | TBC1D12 |
| hsa_circRNA_008289 | hsa_circ_0008289 | 0.007861232 | 0.431741635 | 1.5038783 | chr6 | Exonic | NM_012454 | TIAM2 |
| hsa_circRNA_072654 | hsa_circ_0072654 | 0.004150655 | 0.431741635 | 3.1968303 | chr5 | Exonic | NM_005869 | CWC27 |
| hsa_circRNA_009554 | hsa_circ_0009554 | 0.044334492 | 0.431741635 | 1.5604032 | chr1 | Exonic | NM_007262 | PARK7 |
| hsa_circRNA_030788 | hsa_circ_0030788 | 0.047261899 | 0.431741635 | 1.6207698 | chr13 | Exonic | NM_052867 | NALCN |
| hsa_circRNA_400850 | 0.036097077 | 0.431741635 | 1.650349 | chr11 | Exonic | NM_016146 | TRAPPC4 | |
| hsa_circRNA_404459 | 0.002634492 | 0.431741635 | 1.6303638 | chr1 | Exonic | NM_022778 | CEP85 | |
| hsa_circRNA_102912 | hsa_circ_0058055 | 0.019467222 | 0.431741635 | 1.5068981 | chr2 | Exonic | NM_000465 | BARD1 |
| hsa_circRNA_032891 | hsa_circ_0032891 | 0.031939282 | 0.431741635 | 1.5637739 | chr14 | Exonic | NM_145231 | EFCAB11 |
| hsa_circRNA_401829 | 0.032698187 | 0.431741635 | 1.5255687 | chr17 | Exonic | NM_178509 | STXBP4 | |
| hsa_circRNA_400511 | 0.023801242 | 0.431741635 | 1.6454873 | chr10 | Exonic | NM_014142 | NUDT5 | |
| hsa_circRNA_100726 | hsa_circ_0002456 | 0.025458471 | 0.431741635 | 1.5928692 | chr10 | Exonic | NM_001380 | DOCK1 |
| hsa_circRNA_405372 | 0.039065216 | 0.431741635 | 1.5208354 | chr15 | Sense overlapping | NR_040051 | IQCH-AS1 | |
| hsa_circRNA_007352 | hsa_circ_0007352 | 0.032409473 | 0.431741635 | 4.6954462 | chrX | Exonic | NM_005088 | AKAP17A |
| hsa_circRNA_104639 | hsa_circ_0084669 | 0.048813158 | 0.431741635 | 1.6255475 | chr8 | Exonic | NM_024790 | CSPP1 |
| hsa_circRNA_406194 | 0.003824786 | 0.431741635 | 2.0373362 | chr22 | Sense overlapping | NM_013365 | GGA1 | |
| hsa_circRNA_406445 | 0.039630011 | 0.431741635 | 1.5055446 | chr4 | Intronic | ENST00000264956 | EVC | |
| hsa_circRNA_405571 | 0.038880048 | 0.431741635 | 1.9452313 | chr17 | Exonic | ENST00000589153 | TADA2A | |
| hsa_circRNA_405791 | 0.016540118 | 0.431741635 | 1.5537398 | chr19 | Exonic | NM_006663 | PPP1R13L | |
| hsa_circRNA_104964 | hsa_circ_0006502 | 0.031313741 | 0.431741635 | 1.6161558 | chr9 | Exonic | NM_138778 | DPH7 |
| hsa_circRNA_100631 | hsa_circ_0006148 | 0.012110784 | 0.431741635 | 2.1672149 | chr10 | Exonic | NM_144660 | SAMD8 |
| hsa_circRNA_405746 | 0.023710234 | 0.431741635 | 1.8437062 | chr19 | Exonic | NM_032207 | C19orf44 | |
| hsa_circRNA_101461 | hsa_circ_0034072 | 0.016991154 | 0.431741635 | 1.8499723 | chr15 | Exonic | NM_014608 | CYFIP1 |
| hsa_circRNA_063280 | hsa_circ_0063280 | 0.046069864 | 0.431741635 | 1.5904218 | chr22 | Exonic | NM_012407 | PICK1 |
| hsa_circRNA_405477 | 0.02927257 | 0.431741635 | 1.7238343 | chr16 | Intronic | ENST00000264005 | LCAT | |
| hsa_circRNA_400042 | hsa_circ_0092302 | 0.025102341 | 0.431741635 | 1.5460887 | chr19 | Intronic | ENST00000325327 | LMNB2 |
| hsa_circRNA_040203 | hsa_circ_0040203 | 0.028512125 | 0.431741635 | 1.5408761 | chr16 | Exonic | NM_001605 | AARS |
| hsa_circRNA_076057 | hsa_circ_0076057 | 0.047636875 | 0.431741635 | 1.571403 | chr6 | Exonic | NM_017754 | UHRF1BP1 |
| hsa_circRNA_001729 | hsa_circ_0000691 | 0.048652258 | 0.431741635 | 1.7920519 | chr16 | Antisense | NM_014699 | ZNF646 |
| hsa_circRNA_004738 | hsa_circ_0004738 | 0.043002838 | 0.431741635 | 1.6720137 | chr5 | Exonic | NM_022897 | RANBP17 |
| hsa_circRNA_100559 | hsa_circ_0000219 | 0.014298038 | 0.431741635 | 1.5281119 | chr10 | Exonic | NM_024948 | FAM188A |
| hsa_circRNA_002773 | hsa_circ_0002773 | 0.029869133 | 0.431741635 | 1.5045762 | chr11 | Exonic | NM_002906 | RDX |
| hsa_circRNA_104004 | hsa_circ_0074930 | 0.021445503 | 0.431741635 | 1.9530485 | chr5 | Exonic | NM_003062 | SLIT3 |
| hsa_circRNA_100317 | hsa_circ_0008390 | 0.04490215 | 0.431741635 | 2.1464941 | chr1 | Exonic | NM_022359 | PDE4DIP |
| hsa_circRNA_100707 | hsa_circ_0020313 | 0.029667199 | 0.431741635 | 1.6620556 | chr10 | Exonic | NM_022126 | LHPP |
| hsa_circRNA_102461 | hsa_circ_0003935 | 0.013483506 | 0.431741635 | 1.5061068 | chr19 | Exonic | NM_000068 | CACNA1A |
| hsa_circRNA_060123 | hsa_circ_0060123 | 0.028890929 | 0.431741635 | 1.5685863 | chr20 | Exonic | uc002xdn.1 | CPNE1 |
| hsa_circRNA_404686 | 0.012768084 | 0.431741635 | 1.9349548 | chr1 | Exonic | NM_003272 | GPR137B | |
| hsa_circRNA_101321 | hsa_circ_0002928 | 0.042321436 | 0.431741635 | 1.611344 | chr14 | Exonic | NM_006109 | PRMT5 |
| hsa_circRNA_100536 | hsa_circ_0005379 | 0.041730172 | 0.431741635 | 1.9452874 | chr10 | Exonic | NM_001494 | GDI2 |
| hsa_circRNA_400994 | 0.011009991 | 0.431741635 | 1.5005858 | chr12 | Exonic | uc001syj.2 | ZDHHC17 | |
| hsa_circRNA_103291 | hsa_circ_0006673 | 0.040743075 | 0.431741635 | 1.6483582 | chr3 | Exonic | NM_025265 | TSEN2 |
| hsa_circRNA_102116 | hsa_circ_0003258 | 0.005918665 | 0.431741635 | 1.5865527 | chr17 | Exonic | NM_014897 | ZNF652 |
| hsa_circRNA_102950 | hsa_circ_0058794 | 0.043872376 | 0.431741635 | 1.7071378 | chr2 | Exonic | NM_014914 | AGAP1 |
| hsa_circRNA_020962 | hsa_circ_0020962 | 0.039359099 | 0.431741635 | 1.6353777 | chr11 | Exonic | uc001mai.1 | HBG2 |
| hsa_circRNA_003508 | hsa_circ_0003508 | 0.035035101 | 0.431741635 | 1.9070829 | chr17 | Exonic | NR_036474 | GPATCH8 |
| hsa_circRNA_008609 | hsa_circ_0008609 | 0.037088726 | 0.431741635 | 1.5778959 | chr2 | Exonic | NR_028356 | MRPL30 |
| hsa_circRNA_100632 | hsa_circ_0018905 | 0.044102213 | 0.431741635 | 5.3789756 | chr10 | Exonic | NM_144660 | SAMD8 |
| hsa_circRNA_406475 | 0.042571045 | 0.431741635 | 1.5153569 | chr4 | Intronic | ENST00000264319 | FRYL | |
| hsa_circRNA_401299 | 0.04743786 | 0.431741635 | 1.6724819 | chr14 | Exonic | NM_145231 | EFCAB11 | |
| hsa_circRNA_102025 | hsa_circ_0007542 | 0.04630629 | 0.431741635 | 1.5477632 | chr17 | Exonic | NM_000267 | NF1 |
| hsa_circRNA_001101 | hsa_circ_0001101 | 0.020138729 | 0.431741635 | 1.6929037 | chr2 | Exonic | NM_020830 | WDFY1 |
| hsa_circRNA_012123 | hsa_circ_0012123 | 0.046218436 | 0.431741635 | 1.7972517 | chr1 | Exonic | uc001clf.3 | ATP6V0B |
FDR: false discover rate; FC: fold change.