Fig. 4. Aggregated Q51 exhibits lamination sheets and predominantly lumpy, slab-shaped filaments.

a Representative sections of annotated Q51 filamentous aggregates from cryoET tomograms showing their most common branching/crossover angle (~60°), often in an asterisk-like pattern, and b thicker regions akin to lamination, onside thinner ones. c Subtomogram average of a subpopulation of filament segments (n = 493) exhibiting a lumpy ~7 × 15 nm slab-shaped morphology. Scale bars: 50 nm (a, b), 15 nm, and 7 nm (c).