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. 2021 Jul 8;7:90. doi: 10.1038/s41523-021-00297-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — DMFS10 = distant metastasis free survival at 10 years post diagnosis, (95% CI) = 95% confidence interval, P = p value, N = number of cases in each subgroup, % = percentage of cases within each risk strata, X axis = percent distant metastasis free survival. Open boxes represent primary test DMFS10 by risk group. Solid boxes represent sub-stratification by secondary tests with 95% confidence intervals (bars). Top panel (a) prosigna-trained low risk cases stratified by Oncotype-trained and Mammaprint-trained results. Middle panel (b) prosigna-trained moderate-risk group. Bottom panel (c) prosigna-trained high risk group.