Table 1.
Oocyte and embryo characteristics of IVF and ICSI attempts of the two patients
| Patient | Age | Duration of infertility years | IVF/ICSI attempts | COH protocol | Oocytes retrieved | Fertilized oocytes | Embryos transferred | Outcomes |
|---|---|---|---|---|---|---|---|---|
| II-1 in family 1 | 28 | 2 | 1st IVF | GnRHa | 10 | 6 (3 2PN/2 1PN/1 3PN) | 0 | All the embryos arrested on day 3 |
| 2nd ICSI | Long | 14 | 6 (6 2PN) | 1 | The 2PN zygotes were cleaved to 1 grade II 5-cell stage for transfer but failed to establish pregnancy, 2 grade II 4-cell stage, and the remaining 3 embryos showed arrested on day 3. All embryos arrested during subsequent blastocyst culture | |||
| V-1 in family 2 | 32 | 7 | 1st IVF | GnRHa | 6 | 5 (4 2PN/1 1PN) | 1 | One embryo viable was transferred but failed to establish pregnancy, the remaining embryos arrested at 2 and 6 cells on day 3 |
| 2nd IVF | GnRHa | 5 | 4 (4 2PN) | 0 | The 2PN zygotes were cleaved to 2 grade III 4-cell embryos and two 2-cell stage arrested |