Table 1.
Patient demographics and clinical characteristics at baseline
| Characteristic | CAPA-IVM | p-value | |
|---|---|---|---|
| Fresh embryo transfer (n = 20) | Freeze-only strategy (n = 20) | ||
| Age, years | 30.1 ± 3.3 | 28.70 ± 3.0 | 0.16 |
| Body mass index, kg/m2 | 24.3 ± 5.0 | 23.7 ± 3.9 | 0.70 |
| Anti-Müllerian hormone, ng/mL | 8.83 ± 3.27 | 8.11 ± 4.51 | 0.57 |
| Antral follicle count, n | 55.6 ± 18.6 | 53.3 ± 25.5 | 0.75 |
| Duration of infertility, years | 2 [1, 3] | 2 [1, 3] | 0.73 |
| Type of infertility, n (%) | 0.73 | ||
| Primary | 13/20 (65.0) | 15/20 (75.0) | |
| Secondary | 7/20 (35.0) | 5/20 (25.0) | |
| Number IVF attempts, n (%) | 0.99 | ||
| 1 | 17/20 (85.0) | 17/20 (85.0) | |
| 2 | 3/20 (15.0) | 3/20 (15.0) | |
| Hormonal profile at first visit | |||
| Prolactin, ng/mL | 19.93 ± 12.03 | 18.18 ± 9.22 | 0.61 |
| Testosterone, nmol/L | 1.33 ± 0.57 | 1.39 ± 0.69 | 0.78 |
| SHBG, nmol/L | 32.94 ± 20.85 | 36.78 ± 20.22 | 0.56 |
| TSH, μIU/mL | 2.60 ± 1.17 | 2.14 ± 0.79 | 0.16 |
| DHEA-SO4, μg/mL | 1.97 ± 0.88 | 2.11 ± 1.08 | 0.65 |
| Anti-thyroperoxidase, IU/mL* | 8.22 ± 2.39 | 10.5 ± 03.87 | 0.29 |
| 17-hydroxyprogesterone, ng/mL | 1.10 ± 0.46 | 1.28 ± 0.78 | 0.38 |
| Number of follicles at last ultrasound | 30.9 ± 7.2 | 33.4 ± 18.9 | 0.58 |
| Number of oocytes retrieved | 18.4 ± 10.2 | 18.2 ± 12.7 | 0.96 |
| Number of MII oocytes | 11.8 ± 6.5 | 12.9 ± 10.7 | 0.71 |
| Number of pronuclear stage | 11.6 ± 6.3 | 12.8 ± 10.8 | 0.79 |
Values are mean ± standard deviation, median [interquartile range], or number of patients (%)
DHEA-SO4 dehydroepiandrosterone sulfate; IVF in vitro fertilization; IVM in vitro maturation; MII metaphase II; SHBG sex hormone-binding globulin; TSH thyroid-stimulating hormone
*Excluding one extreme value of 600 IU/mL