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. 2021 Jun 25;8:654250. doi: 10.3389/fmed.2021.654250

Figure 1.

Figure 1

The effects of different nutritional interventions to slow progression of CKD. Schematic representation of reno-protective mechanisms related to protein and diet restriction. These effects can be synergistic with the mechanisms of angiotensin-converting-enzyme inhibitors and angiotensin-receptor blockers, which dilate the efferent arteriole and reduce intraglomerular pressure and glomerular damage. Adapted from Kalantar-Zadeh and Fouque (5). CKD, chronic kidney disease; GFR, glomerular filtration rate; TGF-β, transforming growth factor beta.