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. 2021 Jul 6;17:17448069211024082. doi: 10.1177/17448069211024082

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© The Author(s) 2021

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Overlapped image of (a) bioluminescence and (b) X-ray of the mandible of a Foxn1 mouse 3 weeks after intracardiac injection of MDA-MB-231^LUC+ cancer cells (color-coded counts, sidebar). (c) Location in the left mandible in this animal of the tumor-induced bone lesion (dotted white line). (d) Stained section of the lesion for luciferase (pink) and DAPI (blue). (e) Effects of tumor implantation on the reflexive head withdrawal (T-E vs. T-M) (***=p<0.001). (f) Distribution (in %) of TG recorded afferents per animal per treatment (WT vs. T-E vs. T-M). Scale bar: 1 mm, 100 µm.