Table 1.
Sociodemographic and clinicopathologic characteristics of patients with head and neck squamous cell carcinoma.
| Characteristic | Age <45 years | Age ≥45 years | P-value |
|---|---|---|---|
| (n = 39) | (n = 38) | ||
| Age, years | |||
| Median | 39 | 65.3 | |
| Range | 25–44 | 48–85 | |
| Sex | |||
| Male | 19 | 20 | 0.731 |
| Female | 20 | 18 | |
| Tobacco consumption | |||
| No | 7 | 7 | 0.904 |
| Yes | 29 | 27 | |
| Unknown | 3 | 4 | |
| Alcohol consumption | |||
| No | 17 | 12 | 0.418 |
| Yes | 19 | 20 | |
| Unknown | 3 | 6 | |
| WHO Performance status | |||
| 0 | 27 | 12 | 0.004 |
| 1 | 10 | 17 | |
| 2–3 | 2 | 8 | |
| Unknown | 0 | 1 | |
| T classification | |||
| 1 | 7 | 5 | 0.178 |
| 2 | 11 | 16 | |
| 3 | 9 | 3 | |
| 4 | 10 | 14 | |
| Unknown | 2 | 0 | |
| N classification | |||
| 0 | 11 | 14 | 0.464 |
| 1–3 | 27 | 24 | |
| Unknown | 1 | 0 | |
| M classification | |||
| 0 | 28 | 33 | not evaluable |
| 1 | 0 | 0 | |
| Unknown | 11 | 5 | |
| Anatomic site | |||
| Oropharyngeal | 8 | 8 | 0.953 |
| Non-oropharyngeal | 31 | 30 | |
| Treatment | |||
| Surgery | 9 | 13 | 0.279 |
| Chemotherapy and/or radiotherapy | 15 | 12 | 0.527 |
| Surgery + adjuvant treatment | 15 | 11 | 0.377 |
| No treatment | 0 | 2 | 0.240 |
| HPV status | |||
| HPV16+ | 4 | 5 | 0.967 |
| HPV16− | 35 | 33 | |
| p16 expression | |||
| p16+ | 6 | 4 | 0.768 |
| p16− | 33 | 34 |
HPV, human papillomavirus, WHO, World Health Organization.