Table 1.

Baseline characteristics of patients with acute ischemic stroke (N = 363).

Group	Non-PSD	PSD	P-value*
N	209	154
Age (y), mean ± SD	62.7 ± 10.5	61.9 ± 12.3	0.554
Gender, male n (%)	69 (33.2%)	62 (41.1%)	0.125
BMI (kg/m2)	24.3 ± 9.2	24.1 ± 4.1	0.824
Education (years)	4.3 ± 3.9	4.0 ± 3.5	0.413
Lesion location
Frontal lobe, n (%)	31 (17.5%)	24 (18.0%)	0.904
Parietal lobe, n (%)	17 (9.6%)	11 (8.3%)	0.685
Temporal lobe, n (%)	12 (6.8%)	14 (10.5%)	0.239
Occipital lobe, n (%)	14 (4.5%)	10 (7.5%)	0.899
Basal ganglia, n (%)	78 (44.1%)	75 (56.4%)	0.032*
Cerebellum, n (%)	18 (10.2%)	16 (12.0%)	0.604
Midbrain, n (%)	20 (11.3%)	13 (9.8%)	0.667
Pons, n (%)	29 (16.4%)	21 (15.8%)	0.888
Medulla, n (%)	23 (13.0%)	40 (12.9%)	0.956
History of drinking, n (%)	78 (39.2%)	44 (30.6%)	0.099
History of smoking, n (%)	66 (31.7%)	43 (28.7%)	0.534
History of hypertension, n (%)	150 (72.5%)	111 (72.5%)	0.986
History of diabetes, n (%)	42 (20.4%)	39 (25.5%)	0.253
History of hyperlipidemia, n (%)	17 (8.3%)	17 (11.1%)	0.368
Coronary artery disease, n (%)	18 (8.8%)	8 (5.3%)	0.206
History of a previous stroke, n (%)	19 (9.2)	17 (11.1)	0.556
MMSE, mean ± SD	22.5 ± 5.5	21.1 ± 5.5	0.019*
HAMD, median (IQR)	3 (1–6)	6 (3–9)	0.001*
NIHSS, median (IQR)	2 (1–4)	3.5 (1–6)	<0.001*
mRS, median (IQR)	1 (1–3)	2 (1–4)	<0.001*
BI, median (IQR)	95 (65–100)	60 (40–90)	<0.001*
Unfavorable outcome at baseline, n (%)	32 (11.3%)	51 (33.3%)	<0.001*
Unfavorable outcome at 5-years, n (%)	28 (13.4%)	45 (29.2%)	<0.001*

BMI, body mass index; NIHSS, National Institutes of Health Stroke Scale; mRS, modified Rankin Scale; MMSE, mini mental state examination; BI, modified Barthel Index; IQR, interquartile range; SD, standard deviation; PSD, Post-stroke depression.

^*p < 0.005.