Table 3.

Multivariate adjusted odds ratios for the association between early-onset PSD and unfavorable outcome at 5-years.

		OR	(95%CI)	P-value*
Model 1	Non-PSD	Reference
	Early-onset PSD	2.877	1.609–5.143	<0.001*
Model 2	Non-PSD	Reference
	Early-onset PSD	2.012	1.017–3.084	0.030*
Model 3	Non-PSD	Reference
	Early-onset PSD	2.279	1.179–4.421	0.015*

OR, odds radio; CI, confidence level; PSD, post-stroke depression.

Model 1: adjusted for age, sex, body mass index, history of smoking, and alcohol drinking.

Model 2: adjusted for covariates from Model 1 and further adjusted for education years, baseline NIHSS score, baseline MMSE score.

Model 3: adjusted for covariates from Model 2 and further adjusted for medical history (coronary heart disease, diabetes mellitus, hyperlipidemia, hypertension, stroke).

^*p < 0.005.