Table 5.

Multivariate adjusted odds ratios for the association between early-onset depression severity and unfavorable outcome at 5-year follow-up.

		OR	(95%CI)	P-value*
Model 1	Depression severity, HAMD score	1.126	1.008–1.257	0.036*
Model 2	Depression severity, HAMD score	1.123	0.989–1.277	0.074
Model 3	Depression severity, HAMD score	1.168	1.015–1.345	0.031*

OR, odds radio; CI, confidence level; PSD, post-stroke depression.

Model 1: adjusted for age, sex, body mass index.

Model 2: adjusted for covariates from Model 1 and further adjusted for education years, baseline NIHSS score, baseline MMSE score, history of smoking and alcohol drinking.

Model 3: adjusted for covariates from Model 2 and further adjusted for and medical history (coronary heart disease, diabetes mellitus, hyperlipidemia, hypertension, stroke).

^*p < 0.005.