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. 2021 Jul 8;62(9):12. doi: 10.1167/iovs.62.9.12

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Figure 4. — SREC-Ⅰ neutralizing antibody treatment of A fumigatus–infected mice cornea. SREC-Ⅰ mRNA (A) and protein (B, C) levels were significantly downregulated after anti-SREC-Ⅰ treatment. Clinical scores of anti–SREC-Ⅰ treatment group were significantly lower than the control group at 3 and 5 days p.i., with no difference between groups at 1 day p.i. (D). Representative slit lamp photographs of anti–SREC-Ⅰ (F) and control IgG-treated mice cornea (E). Hematoxylin and eosin staining showed normal cornea (G1), A fumigatus–infected cornea (G2), control IgG treated cornea (G3) and anti–SREC-Ⅰ antibody–treated cornea (G4). Quantitative analysis for the number of inflammatory cells in HE staining (H) (n = 6/group/time). Original magnification ×400. ns, no significance.