Table 1. Clinicopathological characteristics of the whole population and the population involved in the final analysis.
Characteristics | LuM cohort, n (%) | LiM cohort, n (%) | Control cohort, n (%) | P | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Total (n=18) | Analyzed | Total (n=18) | Analyzed | Total/analyzed (n=10) | ||||||
Primary (n=16) | Metastases (n=15) | Primary (n=16) | Metastases (n=18) | |||||||
Sex | 1.000 | |||||||||
Male | 11 (61.1) | 9 (56.3) | 10 (66.7) | 11 (61.1) | 9 (56.3) | 11 (61.1) | 6 (60.0) | |||
Female | 7 (38.9) | 7 (43.8) | 5 (33.3) | 7 (38.9) | 7 (43.8) | 7 (38.9) | 4 (40.0) | |||
Age (years) | 0.661 | |||||||||
Median (range) | 57.5 (35-79) | 57.5 (35-79) | 56 (35-79) | 58 (38-74) | 58 (42-74) | 58 (38-74) | 57 (42-69) | |||
≤60 | 12 (66.7) | 11 (68.8) | 10 (66.7) | 11 (61.1) | 10 (62.5) | 11 (61.1) | 8 (80.0) | |||
>60 | 6 (33.3) | 5 (31.3) | 5 (33.3) | 7 (38.9) | 6 (37.5) | 7 (38.9) | 2 (20.0) | |||
Primary location | 0.124 | |||||||||
Left colon | 2 (11.1) | 2 (12.5) | 2 (13.3) | 2 (11.1) | 2 (12.5) | 2 (11.1) | 4 (40.0) | |||
Rectum | 16 (88.9) | 14 (87.5) | 13 (86.7) | 16 (88.9) | 14 (87.5) | 16 (88.9) | 6 (60.0) | |||
T stage | N/A | |||||||||
T1–2 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |||
T3–4 | 18 (100.0) | 16 (100.0) | 15 (100.0) | 18 (100.0) | 16 (100.0) | 18 (100.0) | 10 (100.0) | |||
N stage | 0.491 | |||||||||
N0 | 2 (11.1) | 2 (12.5) | 2 (13.3) | 2 (11.1) | 2 (12.5) | 2 (11.1) | 3 (30.0) | |||
N1–2 | 16 (88.9) | 14 (87.5) | 13 (86.7) | 16 (88.9) | 14 (87.5) | 16 (88.9) | 7 (70.0) | |||
Histopathologic type | 1.000 | |||||||||
Adenocarcinoma | 17 (94.4) | 16 (100.0) | 14 (93.3) | 17 (94.4) | 15 (93.8) | 17 (94.4) | 10 (100.0) | |||
Mucinous carcinoma/signet ring cell carcinoma ± adenocarcinoma | 1 (5.6) | 0 (0.0) | 1 (6.7) | 1 (5.6) | 1 (6.3) | 1 (5.6) | 0 (0.0) | |||
Differentiation grade | 0.823 | |||||||||
Well to moderate | 14 (77.8) | 14 (87.5) | 11 (73.3) | 14 (77.8) | 12 (75.0) | 14 (77.8) | 7 (70.0) | |||
Poor to undifferentiated | 4 (22.2) | 2 (12.5) | 4 (26.7) | 4 (22.2) | 4 (25.0) | 4 (22.2) | 3 (30.0) |
LuM, lung metastases; LiM, liver metastases; AMP, amplification.