Table 5. Univariate Cox regression analysis of prognostic factors of survival in NSCLC patients.
| Characteristics | Hazard ratio (95% CI) | P value |
|---|---|---|
| Histological subtype | 0.908 (0.757–1.089) | 0.300 |
| Age | 1.536 (1.060–2.226) | 0.023* |
| Gender | 1.064 (0.720–1.571) | 0.756 |
| Tobacco smoking history | 1.157 (0.770–1.737) | 0.482 |
| Tumor size (cm) | 1.252 (0.869–1.802) | 0.227 |
| Lymph node metastasis | 3.522 (2.430–5.105) | <0.001* |
| TNM stage | 2.470 (1.947–3.134) | <0.001* |
| Degree of differentiation | 0.405 (0.239–0.688) | <0.001* |
| USP14 expression | 1.914 (1.301–2.816) | <0.001* |
| PSMD14 expression | 1.967 (1.308–2.957) | 0.001* |
*, P<0.05. NSCLC, non-small cell lung cancer; CI, confidence interval; USP14, ubiquitin specific peptidase 14; PSMD14, proteasome 26S subunit, non-ATPase 14.