Table 3. Lung function and blood characteristics of different HRCT patterns in EGPA.
| Characteristics | Airway pattern (n=57) | Airspace pattern (n=18) | Mixed pattern (n=21) | P value |
|---|---|---|---|---|
| FVC (% predicted) | 82.12±15.36 | 86.75±10.18 | 82.24±23.49 | 0.123 |
| FEV1 (% predicted) | 55.35±19.40 | 63.75±16.22 | 60.37±25.70 | 0.075 |
| FEV1/FVC (%) | 58.09±16.55 | 62.30±13.88 | 59.28±18.42 | 0.087 |
| PEFR (% predicted) | 67.63±23.35 | 73.88±23.65 | 68.81±26.64 | 0.024* |
| MMEF (% predicted) | 24.90 (11.98–35.73) | 35.20 (24.70–59.50) | 25.80 (15.20–36.30) | 0.038* |
| Blood eosinophil count (×109/L) | 0.79 (0.49–1.30) | 0.66 (0.39–1.81) | 1.20 (1.16–1.54) | 0.055 |
| Blood eosinophil (% of white cell count) | 10.80 (6.50–18.30) | 8.40 (5.23–17.18) | 15.40 (11.30–28.70) | 0.073 |
| Total serum IgE (kU/L) | 383.00 (127.00–655.00) | 544.50 (326.75–1,940.25) | 709.00 (416.00–2,294.00) | 0.007# |
Data are presented as mean ± SD, or median (IQR). *, airspace and mixed patterns differed significantly according to the Bonferroni test. Other between-group differences were not statistically significant. #, between-group differences among HRCT patterns were statistically significant according to the Bonferroni test. HRCT, high-resolution computed tomography; EGPA, eosinophilic granulomatosis with polyangiitis; FVC, forced vital capacity; FEV1, forced expiratory volume in the first second; PEFR, peak expiratory flow rate; MMEF, mid-maximal expiratory flow; IgE, immunoglobulin E; SD, standard deviation; IQR, interquartile range.