Table 3. Baseline treatment for pre-existing autoimmune disease (AD) before initiation of Immune check point inhibitor therapy.

Autoimmune Disease	Treatment [number of patients]
Rheumatologic AD
1. Rheumatoid arthritis	MTX alone [1], HCQ alone [1], MTX + HCQ [1], MTX + HCQ + prednisone [1], MTX + infliximab [1]
2. Polymyalgia rheumatica	Prednisone [1]
3. Psoriatic arthritis	Leflunomide + prednisone [1], MTX alone [2]
4. Inflammatory arthritis	HCQ alone
5. Scleroderma	Quinacrine, HCQ, sildenafil
Dermatologic AD
1. Psoriasis	Topical steroids
2. Cutaneous lupus	HCQ
Endocrine
1. Hashimoto’s thyroiditis	Levothyroxine
2. Graves’ disease	Levothyroxine
3. Autoimmune hypophysitis	Hydrocortisone, levothyroxine
4. Type 1 diabetes mellitus	Insulin
Gastrointestinal
1. Crohn’s	Infliximab
Neurologic
1. Myasthenia gravis	Mycophenolate mofetil, pyridostigmine
2. Multiple sclerosis	Interferon beta-1a
3. Chronic inflammatory demyelinating neuropathy	Intravenous immunoglobulin
Others
1. MPGN	Bortezomib then required dialysis

AD, autoimmune disease; HCQ, hydroxychloroquine; MTX, methotrexate; MPGN, membranoproliferative glomerulonephritis.