Table 4. AD exacerbation during ICI therapy.

Characteristic	Patients (n)
Flare of underlying AD
1. Patients who did not develop AD flare	30
2. Patients who developed AD flare	12
Grades of AD flares
1. Grade 1–2	7
2. Grade 3–4	3
3. Grade unknown	2
Treatment required for AD flares
1. No treatment required/supportive care	1
2. Corticosteroids only	8
3. Tofacitinib	1
4. Infliximab	1
5. Plasmapheresis	1
ICI therapy during/after AD flare
• Continued	7
• Permanently discontinued	5

AD, autoimmune disease; ICI, Immune check point inhibitor.