Table 2:
Demographics | |
---|---|
Mean age (years) | 56.07 |
Males | 71 |
Females | 28 |
Average latency of neurological symptoms (days) | 12.2 (±7.5) |
Arboviral symptoms | |
Fever | 67/95 |
Sore throat | 12/95 |
Anosmia/dysgeusia | 25/95 |
Dry cough | 60/95 |
Rash | 2/95 |
Arthralgia/myalgia | 18/95 |
Chest pain | 1/95 |
Shortness of breath | 27/95 |
Headache | 10/95 |
Gastrointestinal symptoms | 17/95 |
Neurological signs and symptoms | |
Dysphagia | 18/99 |
Dysarthria | 11/99 |
Sensory symptoms | 65/99 |
Diplopia | 11/99 |
Facial palsy | 42/99 |
Bulbar palsy | 12/99 |
Ocular palsy | 11/99 |
Tetraparesis | 64/99 |
Paraparesis | 81/99 |
Sensory deficits | 41/99 |
Areflexia or hyporeflexia | 93/99 |
Ataxia | 18/99 |
Respiratory dysfunction | 30/99 |
Dysautonomia | 20/99 |
GBS clinical variant | |
Classical sensorimotor GBS | 64/99 |
Paraparetic GBS | 16/99 |
Miller Fisher syndrome | 9/99 |
Pharyngeal-cervical-brachial GBS | 2/99 |
Bilateral facial palsy with paranesthesia | 3/99 |
Bickerstaff brainstem encephalitis | 0/99 |
Pure motor GBS | 0/99 |
Pure sensory GBS | 1/99 |
Unclassified | 4/99 |
CSF analysis | |
Albuminocytologic dissociation | 74/86 |
Oligoclonal bands | 2/86 |
Normal | 10/86 |
Neuroimaging findings | |
Cranial nerve enhancement | 9/61 |
Spinal nerve root enhancement | 10/61 |
Unremarkable | 44/61 |
Antiganglioside antibodies | |
Anti-GM1 | 3/50 |
Anti-GM2 | 2/50 |
Anti-GD1a | 3/50 |
Anti-GD1b | 3/50 |
Anti-GD3 | 1/50 |
Anti-GQ1b | 1/50 |
Anti-GT1b | 1/50 |
Anti-Gal-C | 1/50 |
Negative antiganglioside Ab | 43/50 |
GBS EMG variant | |
AIDP | 59/77 |
AMAN | 8/77 |
AMSAN | 10/77 |
Immunomodulatory treatment | |
IVIG | 72/98 |
PLEX | 10/98 |
IVIG and PLEX | 7/98 |
No treatment | 8/98 |
Clinical outcome | |
ICU admission | 40/99 |
Mechanical ventilation | 33/99 |
Death | 6/99 |
Brighton criteria | |
Level 1–3 | 84/99 |
Level 4 | 9/99 |
Other variants | 6/99 |
AIDP= acute inflammatory demyelinating polyneuropathy; AMAN=acute motor axonal neuropathy; AMSAN=acute motor and sensory axonal neuropathy; CSF=cerebrospinal fluid; GBS=Guillain Barre syndrome; ICU=intensive care unit; IVIG=intravenous immunoglobulin; PLEX=plasmapheresis.