Table 2.
Phenotypic characteristics and biochemical data in White versus Black women with PCOS.
| White women with PCOS (n = 202) | Black women with PCOS (n = 70) | P value | |
|---|---|---|---|
| Measures of androgen excess | |||
| FG score | 10 (4–15) | 12 (5–17) | .128 |
| Total testosterone (ng/dL) | 49 (32–60) | 48 (44–74) | .055 |
| Free testosterone (pg/mL) | 4.9 (2.5–8) | 6.3 (3.7–9.7) | .086 |
| DHEAS (μg/dL) | 222.5 (136.0–307.0) | 177.5 (118.0–264.8) | .036 |
| SHBG (nmol/L) | 53.5 (31.6–100.9) | 38 (24–67) | .031 |
| Measures of hyperlipidemia | |||
| Total cholesterol (mg/dL) | 179.5 (162–204) | 164 (149–177) | <.001 |
| Triglycerides (mg/dL) | 103.5 (75.5–163.5) | 68 (51–92) | <.001 |
| LDL (mg/dL) | 100 (83–118) | 97 (86–110) | .584 |
| HDL (mg/dL) | 54 (45–67) | 50 (41.5–59) | .043 |
| Measures of insulin resistance | |||
| HgbA1c | 5.3 ± 0.4 | 5.6 ± 0.4 | <.001 |
| HOMA-IR | 2.8 (1.5–5.6) | 3.7 (1.8–6.2) | .334 |
| Fasting glucose | 85 (78–91) | 85 (81–90) | .730 |
| Measures of ovarian reserve | |||
| AMH (ng/mL) | 6.0 (3.1–9.1) | 7.0 (4.4–10.4) | .251 |
| Total AFC | 37 (27–40) | 40 (31–55) | .044 |
Note: Data are presented as median (IQR) and mean ± SD. AFC = antral follicle count; AMH = antimüllerian hormone; DHEAS = dehydroepiandrosterone sulfate; FG = Ferriman-Gallwey score; HDL = high-density lipoprotein; HgbA1c = hemoglobin A1c; HOMA-IR = homeostatic model assessment of insulin resistance; IQR = interquartile range; LDL = low-density lipoprotein; PCOS = polycystic ovary syndrome; SHBG = sex hormone-binding globulin.