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Gene expression of collagen and ECM-related genes in CC mucosa. Normalized log2-transformed fold changes (using the regularized log function in R) of RNA-seq transcript counts. Healthy control subjects (Hc) are shown in green, auCC samples in orange, inactive/treated CC (itCC) samples in blue, and active/refractory CC (aRCC) samples in purple. n = 9–13 samples per group. Statistically significant differences relative to Hc samples are shown as ∗∗P < .01, and ∗∗∗P < .001.
